Shillington - Ireland's most capped player - showed all her experience as she thumped five boundaries in her 39 ball innings, sharing an unbroken opening stand of 75 with Cecelia Joyce as Ireland raced past their modest target of 73 in just 12.5 overs.
Joyce also found the boundary ropes twice in her undefeated 27 from 38 balls, as both batters adjusted well to the sluggish pitch.
Shillington and Joyce both used their feet advancing down the track to the Thailand attack, punishing anything remotely loose.
Earlier, Thailand were restricted to 72 for 7 after opting to bat first. They found runs hard to come by, as a combination of tight bowling backed up by athletic fielding proved hard to penetrate.
Kim Garth (1-8) got an early breakthrough, courtesy of a superb diving catch by wicket-keeper Mary Waldron, and that set the tone for the innings in which the Irish never relinquished their stranglehold on the game.
Leinster all-rounder Laura Delany bowled well claiming 2 for 9, while the spinning triumvirate of Ciara Metcalfe and the Lewis sisters also got among the wickets.
T20 World Cup Qualifier Warm-Up Game
THAILAND WOMEN 72/7 (20 overs, Naruemol Chaiwai 29, L Delany 2-9, G Lewis 1-7, K Garth 1-8, C Metcalfe 1-12, R Lewis 1-15)
IRELAND WOMEN 75/0 (12.5 overs, C Shillington 46*, C Joyce 27*)
Ireland Women beat Thailand Women by 10 wickets